Clinical Neuropsychiatry Volume 22, issue 3 – June 2025

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Polyvagal Theory: Current Status, Clinical Applications, and Future Directions

Stephen Porges Key words: polyvagal theory, ventral vagal complex, neuroception, vagal efficiency, trauma, autonomic nervous system Polyvagal Theory proposes an evolutionarily informed neurophysiological framework for understanding how the autonomic nervous...
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Observing the influence of shame and guilt in inflammatory bowel disease: A systematic review

Marco Cannavò, Rocco Spagnuolo, Janine Gullo, Nadia Barberis Key words: inflammatory bowel disease, crohn’s disease, ulcerative colitis, shame, guilt Objective: Inflammatory Bowel Disease (IBD) is a gastrointestinal condition that significantly impacts...
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EXPLORING CHARACTERISTICS, SERVICES AND OUTCOME INDICATORS OF GLOBAL FUNCTIONING IN ADULTS WITH AUTISM SPECTRUM DISORDERS: INSIGHTS FROM A GROUP OF 503 PATIENTS

Emanuela Nobile, Giovanni Cicinelli, Elisa De Bartolo, Romeo Brambilla, Stefania Brighenti, Roberto Keller Key words: autism, adulthood, outcomes, global functioning, interventions Objective: Autism Spectrum Disorders are neurodevelopmental disorders...
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Medical comorbidities in Alzheimer’s disease: an autopsy confirmed study with a focus on sex-differences?

Antonina Luca, Maria Luca, Raffaele Ferri, Marco Barbanti, Roberta Malaguarnera, Basilio Pecorino, Paolo Scollo, Alessandro Serretti Key words: alzheimer, cardiovascular disorders, endocrinological disorders, lifestyle, depression Objective: Systemic...
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Autistic children and adolescents without intellectual disability: individual and family profile

Daniele de Brito Wanderley, Filippo Muratori, Nayara Argollo, Arthur Tolentino, Tatiane Miranda, Fernanda Vaz, Vania Campos, Adriana Marques de Mattos, Rita Lucena Key words: autism, comorbidities, school inclusion Objective: This study aims to characterize...
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Does Dysregulation of the Indirect Pathway Contribute to the Pathophysiology of Catatonia Through Neurotransmitter Imbalance?

Pegah Seif Key words: catatonia, basal ganglia pathways, gaba, dopamine, glutamate, serotonin, benzodiazepines, pathophysiology, neurotransmitters Objective: Catatonia is a complex neuropsychiatric syndrome characterized by motor, cognitive, and emotional...
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“Too good to be true”: an explorative study of photo manipulation, body image dissatisfaction and critical thinking

Amelia Rizzo, Martina Barbera, Fuat Aydoğdu, Müge Akbağ Key words: digital body image, photo manipulation, critical thinking, selfie Objective: Several studies have demonstrated an increase in body dissatisfaction following the use of photo filters;...
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ADHD and Suicide Risk: The Overlooked Roles of Comorbid Disorders and Stimulant Medications

Yaakov Ophir Key words: ADHD, suicide, comorbid disorders, ADHD medications, stimulant medications Does Attention Deficit Hyperactivity Disorder (ADHD) increase the risk of suicidality among children? This article critically examines a notable study by...