Clinical Neuropsychiatry Volume 22, issue 6 – December 2025

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Genetic Risk, Self-Harm, and Violence in Schizophrenia: A Narrative Review of Implications for Early Identification and Intervention

by Ela Doruk Korkmaz, Elif Everest Objective: This narrative review examines clinical, genetic, and epidemiological evidence on schizophrenia (SCZ) to identify predictors of self-harm and violence, summarize genetic contributors to SCZ including pleiotropy...
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Algorithmic entrapment the silent erosion of user autonomy and mental health

by Leon Donadoni, Donatella Marazziti, Federico Mucci Recent developments in the study of highly visual social media have highlighted that, far from being neutral conduits, adolescents’ online environments might be curated by recommender systems that...
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Profiling teen social networking sites users: developmental, identity, and psychological issues

by Francesca Gioia, Valentina Boursier Objective: in the last decades, social networking sites (SNSs) use among adolescents has dramatically increased, feeding the adolescents’ needs. However, younger users might be more vulnerable to problematic social...
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Development and validation of the Climate Change Anxiety Scale-Short Form

by Maria Mirandi, Giorgio Ghizzoni, Carlo Garofalo, Elisa Delvecchio, Giacomo Rettori, Susan Clayton, Claudia Mazzeschi Objective: this study aimed to provide preliminary validity evidence for an 8-item short form of the Climate Change Anxiety Scale (CCAS-SF)...
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Association between circulating cytokines and psychosomatic syndromes in patients with mood disorders

by Mario Altamura, Livia Ficarella, Ivana Leccisotti, Rossana Laurello, Michele Carapellese, Benedetta Vai, Francesco Benedetti, Antonello Bellomo Objective: elevated levels of pro-inflammatory cytokines are frequently observed in mood disorders, but...
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Development and preliminary validation of a pakistani neuropsychological test assessment battery- PANTAB

by Shameem Fatima, Tehmina Zubair Objective: the main objective of present research project was to develop and validate a neuropsychological test assessment battery to evaluate the neuropsychological profiles of healthy and clinical populations from Pakistani. Method:...
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Pharmacological Interventions for Excoriation Behaviors in Alzheimer's Disease: an Empty Systematic Review of Clinical Trials

by Victor Linking Magalhães Campos, Antonio de Pádua Serafim Objective: skin-picking behaviors are often maintained in association with mood changes, but can also manifest as separate manifestations particularly in Alzheimer's disease (AD). Verifying...
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Gender dysphoria and neurodevelopmental disorders: prevalence of attention deficit hyperactivity disorder (ADHD) among adults with gender dysphoria and their clinical phenotype

by Chiara Cecchelli, Corinna Moradei, Carlotta Cocchetti, Giacomo Grassi Objective: despite the increasing amount of data showing the presence of high association between gender dysphoria (GD) and autism spectrum disorders, less is known on the association...
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Physiological and personality measures as potential factors associated with Cardiac Coherence Training effects on symptoms reduction: A pilot study on healthcare workers

by Sara Guidotti Objective: high cardiovascular risk (i.e., increased heart rate (HR) and reduced HR variability (HRV)) is common among healthcare workers. HRV biofeedback (HRVB) and cardiac coherence training (CCT) aim to minimize cardiac reactivity...
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Stratifying the inflamed endotype in Difficult-to-Treat Depression: A roadmap from biomarkers to precision immunopsychiatry

by Walter Paganin Difficult-to-treat depression (DTD) extends beyond pharmacological non-response to encompass persistent symptoms, disability, and functional impairment despite optimal therapeutic strategies. This opinion advances a paradigm-shifting...